Characterising Mechanisms of Ischemia in Patients with Myocardial Bridges.

ABSTRACT: Background: Myocardial bridges (MBs) are prevalent and can be associated with acute and chronic ischemic syndromes. We sought to determine the substrates for ischemia in patients with angina, nonobstructive coronary arteries (ANOCA) and a MB in the left anterior descending artery. Methods: Patients with ANOCA underwent acquisition of intracoronary pressure and flow during rest, supine bicycle exercise and adenosine infusion. Coronary wave intensity analysis was performed, with perfusion efficiency defined as accelerating wave energy/total wave energy (%). Epicardial endothelial dysfunction was defined as a reduction in epicardial vessel diameter ≥20% in response to intracoronary acetylcholine infusion. Patients with ANOCA and a MB were compared to two ANOCA groups with no MB:

SUBMITTER: Sinha A 

PROVIDER: S-EPMC10782941 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature