Co-PATHOgenex web application for assessing complex stress responses in pathogenic bacteria.

ABSTRACT:

Importance

Unveiling gene co-expression networks in bacterial pathogens has the potential for gaining insights into their adaptive strategies within the host environment. Here, we developed Co-PATHOgenex, an interactive and user-friendly web application that enables users to construct networks from gene co-expressions using custom-defined thresholds (https://avicanlab.shinyapps.io/copathogenex/). The incorporated search functions and visualizations within the tool simplify the usage and facilitate the interpretation of the analysis output. Co-PATHOgenex also includes stress stimulons for various bacterial species, which can help identify gene products not previously associated with a particular stress condition.

SUBMITTER: Fernandez L 

PROVIDER: S-EPMC10783046 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature