Comprehensive, comparative evaluation of 25 automated SARS-CoV-2 serology assays.

ABSTRACT:

Importance

We have previously highlighted the fact that hundreds of SARS-CoV-2 serology tests were released months after the onset of the COVID-19 pandemic. Of the hundreds of studies investigating the test kits' performance, few were comparative reports, using the same comprehensive sample set across multiple tests. Recently, we reported a comparative assessment of 35 rapid diagnostic tests (RDTs) or microtiter plate enzyme immunoassays (EIA) for use in low- and middle-income countries, using a large sample set from individuals with a history of COVID-19. Only a few tests meet WHO Target Product Profile performance requirements. This study reports on the performance of a further 25 automated SARS-CoV-2 immunoassays using the same panel of samples. The results highlight the better

SUBMITTER: Dimech W 

PROVIDER: S-EPMC10783060 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature