Bloodstream infections after solid organ transplantation: clinical epidemiology and antimicrobial resistance (2016-21).

ABSTRACT:

Background

Solid organ transplant (SOT) recipients are at risk of bloodstream infections (BSIs) with MDR organisms (MDROs).

Objectives

To describe the epidemiology of BSI in the year after several types of SOT, as well as the prevalence of MDRO infections in this population.

Methods

We conducted a single-centre, retrospective study of kidney, liver, heart, and multi-organ transplantation patients. We examined BSIs ≤1 year from SOT and classified MDRO phenotypes for Staphylococcus aureus, enterococci, Enterobacterales, Pseudomonas aeruginosa and Candida spp. We compared BSI characteristics between SOT types and determined risk factors for 90 day mortality.

Results

We included 2293 patients [1251 (54.6%) kidney, 663 (28.9%) liver, 219 (9.6%)

SUBMITTER: Adelman MW 

PROVIDER: S-EPMC10783261 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature