FLAMS: Find Lysine Acylations and other Modification Sites.

ABSTRACT:

Summary

Today, hundreds of post-translational modification (PTM) sites are routinely identified at once, but the comparison of new experimental datasets to already existing ones is hampered by the current inability to search most PTM databases at the protein residue level. We present FLAMS (Find Lysine Acylations and other Modification Sites), a Python3-based command line and web-tool that enables researchers to compare their PTM sites to the contents of the CPLM, the largest dedicated protein lysine modification database, and dbPTM, the most comprehensive general PTM database, at the residue level. FLAMS can be integrated into PTM analysis pipelines, allowing researchers to quickly assess the novelty and conservation of PTM sites across species in newly generated datasets, aiding

SUBMITTER: Longin H 

PROVIDER: S-EPMC10783949 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature