Relationship between GCKR gene rs780094 polymorphism and type 2 diabetes with albuminuria.

ABSTRACT:

Background

Diabetic kidney disease is one of the common complications of type 2 diabetes (T2D). There are no typical symptoms in the early stage, and the disease will progress to moderate and late stage when albuminuria reaches a high level. Treatment is difficult and the prognosis is poor. At present, the pathogenesis of diabetic kidney disease is still unclear, and it is believed that it is associated with genetic and environmental factors.

Aim

To explore the relationship between the glucokinase regulatory protein (GCKR) gene rs780094 polymorphism and T2D with albuminuria.

Methods

We selected 252 patients (126 males and 126 females) with T2D admitted to our hospital from January 2020 to October 2020, and 66 healthy people (44 females and 22 males). According

SUBMITTER: Liu YY 

PROVIDER: S-EPMC10784796 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature