Adjuvant Chemotherapy and Outcomes in Older Adult Patients With Biliary Tract Cancer.

ABSTRACT:

Importance

The association of adjuvant chemotherapy (AC) with survival in the general population of patients with resected biliary tract cancer (BTC) remains controversial. As such, the role of this treatment in the treatment of older adult patients (aged ≥70 years) needs to be evaluated.

Objective

To describe the patterns of use of AC and compare survival outcomes of AC and observation in older adult patients following resection of BTC.

Design, setting, and participants

This retrospective cohort study included 8091 older adult patients with resected BTC with data available in the National Cancer Database from January 1, 2004, to December 31, 2019. Patients were divided into 2 cohorts: AC and observation. The AC cohort was subdivided into single-agent and multiagent A

SUBMITTER: Gbolahan OB 

PROVIDER: S-EPMC10784855 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature