Childhood Trauma, Emotional Awareness, and Neural Correlates of Long-Term Nicotine Smoking.

ABSTRACT:

Importance

Temporal dynamic measures provide insight into the neurobiological properties of nicotine use. It is critical to determine whether brain-based measures are associated with substance use risk factors, such as childhood trauma-related emotion dysregulation.

Objective

To assess temporal dynamic differences based on smoking status and examine the associations between childhood trauma, alexithymia, nicotine smoking, and default mode network (DMN) states.

Design, setting, and participants

This cross-sectional study was conducted in the Baltimore, Maryland, area at the National Institute on Drug Abuse. Participants included individuals aged 18 to 65 years who smoked nicotine long term and matched controls with no co-occurring substance use or psychiatric disorders

SUBMITTER: Quam A 

PROVIDER: S-EPMC10784870 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature