Expert Revision of Key Elements for Clinical-Grade Production and Qualification of Perinatal Derivatives.

ABSTRACT: Perinatal derivatives have been proposed as adjunct therapeutic strategies or innovative treatments. Undoubtedly, perinatal derivatives can offer the opportunity and source material to isolate multipotent stem cells, but both maternal- and fetal-derived tissues can be processed and transformed into engineered tissues or advanced biomedical devices, whose potential remains to be fully elucidated. Promising preclinical and clinical results collected so far clearly foresee an escalation of such novel treatments. Market forecasts predict exponential growth in such advanced medicinal products during the next decade, with a pragmatic innovation for medicine into a more advanced biomedical version, enlarging the portfolio for treating a wide range of congenital and acute conditions. However, all

SUBMITTER: Gramignoli R 

PROVIDER: S-EPMC10785218 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature