Impact of Helicobacter pylori colonization density and depth on gastritis severity.

ABSTRACT:

Background and objectives

Helicobacter pylori (H. pylori) infection is the most common etiology of chronic gastric. H. pylori gastritis would gradually evolve into gastric atrophy, intestinal metaplasia, dysplasia and malignant lesions. Herein, this study aimed to investigate the potential impact of H. pylori colonization density and depth on the severity of histological parameters of gastritis.

Methods

A prospective monocentric study was conducted from December 2019 to July 2022, enrolling patients with confirmed chronic H. pylori infection via histopathological evaluation. H. pylori colonization status was detected by immunohistochemical staining, pathological changes of gastric specimens were detected by hematoxylin eosin staining. Epidemiological, endoscopic and histopat

SUBMITTER: Peng J 

PROVIDER: S-EPMC10785438 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature