Association between obesity, physical activity, and cognitive decline in Chinese middle and old-aged adults: a mediation analysis.

ABSTRACT:

Background and objectives

Epidemiological evidence on obesity and cognitive decline in middle and old-aged individuals is controversial and the effect of physical activity in this chain is sparse and limited. This study aimed to characterize the association between obesity and cognitive decline and the mediating role of physical activity.

Methods

Data from China Health and Retirement Longitudinal Study (CHARLS) were used, including 7,392 participants aged ≥ 45 years between 2011 and 2018. Cognitive function was assessed via episodic memory and mental status. The total score of cognitive function was the sum of the above two dimensions (0-31 points). The Group-based trajectory modeling (GBTM) was applied to identify the potential heterogeneity of longitudinal changes in cogni

SUBMITTER: Xu X 

PROVIDER: S-EPMC10785530 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature