Estimates of early outbreak-specific SARS-CoV-2 epidemiological parameters from genomic data.

ABSTRACT: We estimate the basic reproductive number and case counts for 15 distinct Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreaks, distributed across 11 populations (10 countries and one cruise ship), based solely on phylodynamic analyses of genomic data. Our results indicate that, prior to significant public health interventions, the reproductive numbers for 10 (out of 15) of these outbreaks are similar, with median posterior estimates ranging between 1.4 and 2.8. These estimates provide a view which is complementary to that provided by those based on traditional line listing data. The genomic-based view is arguably less susceptible to biases resulting from differences in testing protocols, testing intensity, and import of cases into the community of interest. In the analys

SUBMITTER: Vaughan TG 

PROVIDER: S-EPMC10786264 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature