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Predicting fetal alcohol spectrum disorders in preschool-aged children from early life factors.


ABSTRACT:

Background

Early life factors, including parental sociodemographic characteristics, pregnancy exposures, and physical and neurodevelopmental features measured in infancy are associated with fetal alcohol spectrum disorders (FASD). The objective of this study was to evaluate the performance of a classifier model for diagnosing FASD in preschool-aged children from pregnancy and infancy-related characteristics.

Methods

We analyzed a prospective pregnancy cohort in Western Ukraine enrolled between 2008 and 2014. Maternal and paternal sociodemographic factors, maternal prenatal alcohol use and smoking behaviors, reproductive characteristics, birth outcomes, infant alcohol-related dysmorphic and physical features, and infant neurodevelopmental outcomes were used to predict FASD. D

SUBMITTER: Bandoli G 

PROVIDER: S-EPMC10786333 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature