PIEZO2 expression is an independent biomarker prognostic for gastric cancer and represents a potential therapeutic target.

ABSTRACT: Gastric cancer (GC) is one of the most prevalent malignant tumors of the gastrointestinal system in the globe. The effect of PIEZO2 on the immune function and pathological features of gastric cancer remains to be explored. The Online database of cancer genes and GSE54129 have been used to analyze the clinical characteristics of PIEZO2 expression. We looked at the relationship between PIEZO2 and the immune systems of GC patients. The TIDE algorithm was used to explore the value of PIEZO2 in immunotherapy. Investigated the enrichment of PIEZO2 gene ontology and associated signal pathways using Online gene databases. The results show that overexpression of PIEZO2 was identified as an independent risk factor for patients with GC who had poor overall survival. Individuals may have a better prog

SUBMITTER: Zhang YC 

PROVIDER: S-EPMC10786914 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature