The First Crested Duck Genome Reveals Clues to Genetic Compensation and Crest Cushion Formation.

ABSTRACT: The Chinese crested (CC) duck is a unique indigenous waterfowl breed, which has a crest cushion that affects its survival rate. Therefore, the CC duck is an ideal model to investigate the genetic compensation response to maintain genetic stability. In the present study, we first generated a chromosome-level genome of CC ducks. Comparative genomics revealed that genes related to tissue repair, immune function, and tumors were under strong positive selection, indicating that these adaptive changes might enhance cancer resistance and immune response to maintain the genetic stability of CC ducks. We also assembled a Chinese spot-billed (Csp-b) duck genome, and detected the structural variations (SVs) in the genome assemblies of three ducks (i.e., CC duck, Csp-b duck, and Peking duck). Function

SUBMITTER: Chang G 

PROVIDER: S-EPMC10787023 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature