Construction and dosimetric characterization of a motorized scanning-slit system for electron FLASH experiments.

ABSTRACT:

Background

Beam scanning is a useful technique for the treatment of large tumors when the primary beam size is limited, which is the case with radiation beams used in FLASH radiotherapy.

Purpose

To optimize beam scanning as a dose delivery method for FLASH radiotherapy, it is necessary to first understand the effects of beam scanning on the FLASH effect. To do so, biological FLASH experiments need to be done using defined beam parameters with beam scanning and compared to the situation without beam scanning. In this regard, we propose implementation of a simple slit scanning system with an electron FLASH beam to obtain a scanned radiation field that closely resembles a static field.

Methods

A pulsed electron linear accelerator (linac) was used in combination with a sc

SUBMITTER: Oesterle R 

PROVIDER: S-EPMC10787038 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature