Sex differences in the association between insulin resistance and non-fatal myocardial infarction across glycaemic states.

ABSTRACT:

Background

Females are generally less prone to cardiovascular (CV) events than males, but this protection is trumped by diabetes. The mechanism behind the increased relative risk in females with diabetes is not fully understood. Insulin resistance (IR) is suggested to be a more important contributor to CV morbidity in females than in males. We aim to investigate differences in the association between IR indexes (Homeostatic Model Assessment of IR - HOMA-IR, visceral adiposity index - VAI, and triglycerides/high-density lipoprotein-cholesterol - TG/HDL-C index), and a first non-fatal myocardial infarction (MI) across different glycaemic states.

Methods

IR indexes were calculated in a population with (n = 696) and without (n = 707) a first non-fatal MI, free from known diabete

SUBMITTER: Riccio A 

PROVIDER: S-EPMC10787422 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature