Treatment persistence and switching patterns of ABP 501 in European patients with inflammatory bowel disease.

ABSTRACT:

Background

Approval of the adalimumab (ADA) biosimilar ABP 501 for inflammatory bowel disease (IBD) indications was based on the principle of extrapolation, without indication-specific clinical trial data.

Objectives

To evaluate the real-world treatment patterns of ABP 501 in patients with IBD.

Design

Retrospective analysis of pharmacy claims data from Germany and France.

Methods

Continuously insured adult IBD patients who initiated ABP 501 between October 2018 and March 2020 were included. Treatment persistence, adherence, and post-ABP 501 switching patterns were evaluated for two mutually exclusive groups: ADA-naïve patients (i.e. no baseline use of ADA products) and ADA-experienced patients (i.e. previously treated with ADA products).

Results

A total

SUBMITTER: Jin R 

PROVIDER: S-EPMC10787526 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature