Acoustic resolution photoacoustic Doppler flowmetry for assessment of patient rectal cancer blood perfusion.

ABSTRACT:

Significance

Photoacoustic Doppler flowmetry offers quantitative blood perfusion information in addition to photoacoustic vascular contrast for rectal cancer assessment.

Aim

We aim to develop and validate a correlational Doppler flowmetry utilizing an acoustic resolution photoacoustic microscopy (AR-PAM) system for blood perfusion analysis.

Approach

To extract blood perfusion information, we implemented AR-PAM Doppler flowmetry consisting of signal filtering and conditioning, A-line correlation, and angle compensation. We developed flow phantoms and contrast agent to systemically investigate the flowmetry's efficacy in a series of phantom studies. The developed correlational Doppler flowmetry was applied to images collected during in vivo AR-PAM for post-treatm

SUBMITTER: Kou S 

PROVIDER: S-EPMC10787588 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature