IgG antibody response to SARS-CoV-2 infection and its influencing factors in lymphoma patients.

ABSTRACT:

Background

The ability of generating effective humoral immune responses to SARS-CoV-2 infection has not been clarified in lymphoma patients. The study aimed to investigate the antibody (Ab) production after SARS-Cov-2 infection and clarify the factors affecting the Ab generation in these patients.

Patients & methods

80 lymphoma patients and 51 healthy controls were included in this prospective observational study. Clinical factors and treatment regimens affecting Ab positive rate (APR) and Ab levels were analyzed by univariate and multivariate methods.

Results

The anti-SARS-CoV-2 IgG APR and Ab levels in lymphoma patients were significantly lower than those in healthy controls. Lymphoma patients with COVID-19 vaccination had significantly higher APR and Ab levels comp

SUBMITTER: Xie H 

PROVIDER: S-EPMC10788029 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature