The use of inhibition assay in Api g 7 suspected allergy in a female patient with anaphylaxis: A case report.

ABSTRACT: The symptoms of celery allergy are mainly presented as oral allergy symptom, but there are several case reports of patients who experienced anaphylaxis. Defensin (Api g 7), as a novel allergen in celery root, was described in 2022 r. The female patient had a history of several episodes of dyspnea and cough, associated with ingestion of spice mixes containing dried celery. Up to the point of hospitalization, there were no objective tests, either sIgE or skin prick tests, that would confirm celery sensitization. During hospitalization, patient had a positive double-blind placebo-controlled food challenge with cooked celery. The patient was sensitized to mugwort defensin Art v 1. An inhibition assay with celery allergen extract was performed to prove cross-sensitization between Art v 1 and ce

SUBMITTER: Ukleja-Sokolowska N 

PROVIDER: S-EPMC10788074 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature