In vitro influence of PEG functionalized ZnO-CuO nanocomposites on bacterial growth.

ABSTRACT: Polyethyleneglycol-coated biocompatible CuO-ZnO nanocomposites were fabricated hydrothermally varying Zn:Cu ratios as 1:1, 2:1, and 1:2, and their antibacterial activity was determined through the well diffusion method against the Gram-negative Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, and the Gram-positive Staphylococcus aureus. The minimum inhibitory concentration and the minimum bactericidal concentration values of the synthesized samples were determined. Subsequently, the time synergy kill assay was performed to elucidate the nature of the overall inhibitory effect against the aforementioned bacterial species. The mean zone of inhibition values for all four samples are presented. The inhibitory effect increased with increasing concentration of the nanocomposite (

SUBMITTER: Jayanetti M 

PROVIDER: S-EPMC10788344 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature