Functional decoding and meta-analytic connectivity modeling in thyroid-associated ophthalmopathy.

ABSTRACT:

Background

Thyroid-associated ophthalmopathy (TAO) is an orbital disease closely related to thyroid disease with a long-lasting duration that can be blinding and disabling. Recently, structural and functional neuroimaging studies have been performed in TAO patients, but studies have reported inconsistent results. This quantitative meta-analysis was conducted to identify convergent patterns of abnormal brain function among different studies in TAO.

Methods

We searched PubMed, EMBASE, Cochrane, and Web of Science, performed reference tracking, and retrieved 15 eligible studies. Peak coordinates were extracted from these studies and subsequently tested for convergence using activation likelihood estimation (ALE).

Results

Compared to healthy subjects, resting-state brain

SUBMITTER: Duan Q 

PROVIDER: S-EPMC10788440 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature