Eyeless razor clam Sinonovacula constricta discriminates light spectra through opsins to guide Ca²⁺ and cAMP signaling pathways.

ABSTRACT: Phototransduction is based on opsins that drive distinct types of Gα cascades. Although nonvisual photosensitivity has long been known in marine bivalves, the underlying molecular basis and phototransduction mechanism are poorly understood. Here, we introduced the eyeless razor clam Sinonovacula constricta as a model to clarify this issue. First, we showed that S. constricta was highly diverse in opsin family members, with a significant expansion in xenopsins. Second, the expression of putative S. constricta opsins was highly temporal-spatio specific, indicating their potential roles in S. constricta development and its peripheral photosensitivity. Third, by cloning four S. constricta opsins with relatively higher expression (Sc_opsin1, 5, 7, and 12), we found that they exhibited different

SUBMITTER: Kong F 

PROVIDER: S-EPMC10788561 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature