Novel strategy for multi-material 3D bioprinting of human stem cell based corneal stroma with heterogenous design.

ABSTRACT: Three-dimensional (3D) bioprinting offers an automated, customizable solution to manufacture highly detailed 3D tissue constructs and holds great promise for regenerative medicine to solve the severe global shortage of donor tissues and organs. However, uni-material 3D bioprinting is not sufficient for manufacturing heterogenous 3D constructs with native-like microstructures and thus, innovative multi-material solutions are required. Here, we developed a novel multi-material 3D bioprinting strategy for bioprinting human corneal stroma. The human cornea is the transparent outer layer of your eye, and vision loss due to corneal blindness has serious effects on the quality of life of individuals. One of the main reasons for corneal blindness is the damage in the detailed organization of the c

SUBMITTER: Puistola P 

PROVIDER: S-EPMC10788621 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature