Fatty acid-binding protein-3 and renal function decline in patients with chronic coronary syndrome.

ABSTRACT:

Background

Renal dysfunction is common in patients with coronary artery disease. Due to the shared vascular pathogenesis between the two conditions, novel biomarkers such as the fatty acid-binding protein-3 (FABP-3) have been proposed for diagnosis and prognosis prediction. This multicentre prospective cohort study investigates the association between FABP-3 and renal dysfunction.

Hypothesis

We hypothesized that higher FABP-3 levels are correlated to worse renal outcome.

Methods

Patients with chronic coronary syndrome were classified into three groups based on the initial serum FABP-3 levels. The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation was used to estimate the patient's renal function. Renal events were defined as >25% and >50% decline in

SUBMITTER: Yeh JT 

PROVIDER: S-EPMC10788638 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature