Clinical value and mechanistic analysis of HIIT on modulating risk and symptoms of depression: A systematic review.

ABSTRACT:

Background

The exact causal mechanisms of depression remain unclear due to the complexity of the triggers, which has led to limitations in treating depression using modern drugs. High-intensity interval training (HIIT) is as effective as medication in treating depression without toxic side effects. Typically, HIIT requires less time commitment (i.e., shorter exercise duration) and exhibits pronounced benefits on depressive symptoms than other forms of physical exercise. This review summarizes the risk reduction and clinical effects of HIIT for depression and discusses the underlying mechanisms, providing a theoretical basis for utilizing HIIT in treating depression.

Methods

A database search was conducted in PubMed, Embase, Web of Science, and Scopus from inception up to Oct

SUBMITTER: Xu Y 

PROVIDER: S-EPMC10788816 | biostudies-literature | 2024 Jan-Mar

REPOSITORIES: biostudies-literature