Association of systemic immunity-inflammation index with metabolic syndrome in U.S. adult: a cross-sectional study.

ABSTRACT:

Background

Metabolic syndrome (MetS) is a pathological condition characterized by the abnormal clustering of several metabolic components and has become a major public health concern. We aim to investigate the potential link of Systemic immunity-inflammation index (SII) on MetS and its components.

Methods and result

Weighted multivariable logistic regression was conducted to assess the relationship between SII and MetS and its components. Restricted cubic spline (RCS) model and threshold effect analysis were also performed. A total of 6,999 U.S. adults were enrolled. Multivariate model found that SII were positively associated with MetS (OR = 1.18;95CI%:1.07-1.30) and hypertension (OR = 1.22; 95CI%:1.12-1.34) in a dose-dependent manner. When SII was converted into a categori

SUBMITTER: Zeng P 

PROVIDER: S-EPMC10788994 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature