The intra-individual reliability of ¹ H-MRS measurement in the anterior cingulate cortex across 1 year.

ABSTRACT: Magnetic resonance spectroscopy (MRS) is the primary method that can measure the levels of metabolites in the brain in vivo. To achieve its potential in clinical usage, the reliability of the measurement requires further articulation. Although there are many studies that investigate the reliability of gamma-aminobutyric acid (GABA), comparatively few studies have investigated the reliability of other brain metabolites, such as glutamate (Glu), N-acetyl-aspartate (NAA), creatine (Cr), phosphocreatine (PCr), or myo-inositol (mI), which all play a significant role in brain development and functions. In addition, previous studies which predominately used only two measurements (two data points) failed to provide the details of the time effect (e.g., time-of-day) on MRS measurement within subjec

SUBMITTER: Wang MY 

PROVIDER: S-EPMC10789202 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature