Polygenic pathogen networks influence transcriptional plasticity in the Arabidopsis-Botrytis pathosystem.

ABSTRACT: Bidirectional flow of information shapes the outcome of the host-pathogen interactions and depends on the genetics of each organism. Recent work has begun to use co-transcriptomic studies to shed light on this bidirectional flow, but it is unclear how plastic the co-transcriptome is in response to genetic variation in both the host and pathogen. To study co-transcriptome plasticity, we conducted transcriptomics using natural genetic variation in the pathogen, Botrytis cinerea, and large-effect genetic variation abolishing defense signaling pathways within the host, Arabidopsis thaliana. We show that genetic variation in the pathogen has a greater influence on the co-transcriptome than mutations that abolish defense signaling pathways in the host. Genome-wide association mapping using the p

SUBMITTER: Krishnan P 

PROVIDER: S-EPMC10789313 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature