Factors Associated with Respiratory Health and Function in Duchenne Muscular Dystrophy: A Systematic Review and Evidence Grading.

ABSTRACT:

Background

Despite advances in the medical management of the disease, respiratory involvement remains a significant source of morbidity and mortality in children and adults with Duchenne muscular dystrophy (DMD).

Objective

The objective of this systematic literature review was to synthesize and grade published evidence of factors associated with respiratory health and function in DMD.

Methods

We searched MEDLINE, Embase, and the Cochrane Library for records of studies published from January 1, 2000 (to ensure relevance to current care practices), up until and including December 31, 2022, reporting evidence of prognostic indicators and predictors of disease progression in DMD. The quality of evidence (i.e., very low to high) was assessed using the Grading of Recommenda

SUBMITTER: Landfeldt E 

PROVIDER: S-EPMC10789346 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature