A Multicenter Analysis of Clinical Features and Long-Term Outcomes of POEMS Syndrome in Korea.

ABSTRACT:

Background

POEMS syndrome is a rare form of plasma cell dyscrasia characterized by polyneuropathy, organomegaly, endocrinopathy, monoclonal proteins, and skin changes. Owing to its low incidence, there are few reports regarding this syndrome. This multicenter study included 84 patients diagnosed with POEMS syndrome in South Korea.

Methods

We retrospectively evaluated 84 patients diagnosed with POEMS syndrome at 8 hospitals in South Korea between January 2000 and October 2022. The clinical characteristics and treatment outcomes were analyzed.

Results

The median patient age was 53 years (range, 26-77 years), and 63.1% of the patients were male. All patients had peripheral neuropathy, and 81 (96.4%) had monoclonal plasma cell proliferation. Plasma vascular endothelial gr

SUBMITTER: Kook HW 

PROVIDER: S-EPMC10789530 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature