Reciprocal crosslink among MeCP2/BDNF /CREB signaling pinpointed in autism spectrum disorder.

ABSTRACT: Autism spectrum disorder, or individual disability (ID), is a condition characterized by complications in social interaction, restricted repetitive behavior, and difficulties in social communication. Neuquinon (NQ) possess a powerful therapeutic potential in various neurodegenerative disease. Nevertheless, contributing to NQ's low water solubility and bioavailability, its medicinal use has been constrained. Liposomes were supposed to be prospective drug-delivering agents for NQ, crossing the blood-brain barrier (BBB), and reaching the target organs. The current investigation aims to track the signaling pathways that govern NQ and liposomal neuquinon (LNQ) action in autistic models generated by ethyl formic acid. The neurotransmitters gamma amino-butyric acid (GABA), acetylcholine (ACh), an

SUBMITTER: Mahmoud AH 

PROVIDER: S-EPMC10789594 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature