Predicting the ovarian response: towards a determinant model and implications for practice.

ABSTRACT:

Objective

To improve the reliability of prediction models for ovarian response to stimulation in ART.

Design

A multicenter retrospective cohort study.

Setting

Twelve reproductive centers.

Patients

A total of 25,854 controlled ovarian stimulations between 2005 and 2016, including cycles cancelled for inadequate response, were included.

Intervention(s)

None.

Main outcome measure(s)

Precision of the prediction of the number of oocytes at ovarian pickup and of cancellation rate for poor ovarian response.

Results

Both AMH and antral follicle count exhibit a non-linear effect on the oocyte yield, with a linear relationship after log-transformation. After adjustment for age, BMI, and center, ovarian response observed in a previous stimulation was

SUBMITTER: Arvis P 

PROVIDER: S-EPMC10789711 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature