MRI characteristics and oncological follow-up of patients with ISUP grade group 4 or 5 prostate cancer.

ABSTRACT:

Objectives

To analyze multiparametric MRI (mpMRI) characteristics of patients with International Society of Urological Pathology (ISUP) grade group (GG) 4 or 5 prostate cancer (PC) and to correlate MRI parameters with the occurrence of biochemical recurrence (BCR) after radical prostatectomy (RPE).

Methods

In this single-center cohort study consecutive patients with mpMRI and ISUP GG 4 or 5 PC were retrospectively analyzed. Clinical, MR-guided biopsy, and diagnostic mpMRI parameter were assessed. A subcohort of patients with RPE and follow-up was analyzed separately. A univariate and multivariate analyses were performed to determine parameters that are associated to patients with BCR after RPE.

Results

145 patients (mean age 70y, median PSA 10.9 ng/ml) were analyzed.

SUBMITTER: Boschheidgen M 

PROVIDER: S-EPMC10789849 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature