Antihypertensive medication nonadherence and target organ damage in children with chronic kidney disease.

ABSTRACT:

Background

Nonadherence is common in children with chronic kidney disease (CKD). This may contribute to inadequate blood pressure control and adverse outcomes. This study examined associations between antihypertensive medication nonadherence, ambulatory blood pressure monitoring (ABPM) parameters, kidney function, and cardiac structure among children with CKD.

Methods

We performed secondary analyses of data from the CKD in Children (CKiD) study, including participants with treated hypertension who underwent ABPM, laboratory testing, and echocardiography biannually. Nonadherence was defined by self-report of any missed antihypertensive medication 7 days prior to the study visit. Linear regression and mixed-effects models were used to assess the association of nonadherence wit

SUBMITTER: Byfield RL 

PROVIDER: S-EPMC10790151 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature