Ambient ozone pollution impairs glucose homeostasis and contributes to renal function decline: Population-based evidence.

ABSTRACT: Particulate matter pollution could increase the risk of kidney disease, while evidence for ozone exposure is less well-established. Here, we aimed to evaluate the effect of ozone pollution on renal function and explore mechanisms. We first conducted a cross-sectional study based on Wuhan Chronic Disease Cohort Study baseline information. We recruited 2699 eligible participants, estimated their residential ozone concentrations, collected fasting peripheral blood samples for biochemical analysis and calculated the estimated glomerular filtration rate (eGFR). The linear regression model was applied to evaluate the long-term association between ozone pollution and eGFR. Then, we recruited another 70 volunteers as a panel with 8 rounds follow-up visits. We calculated the eGFR and measured fasti

SUBMITTER: Peng S 

PROVIDER: S-EPMC10790241 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature