Genetic variants in the TAC1 transcriptional regulatory region affect on trainability and excitability levels in Belgian Malinois dogs.

ABSTRACT:

Background

Trainability in dogs is affected by learning aptitude and memory capacity. While this trait has a heritable basis in canines, the specific genetic loci responsible for it remain unknown. Our previous results suggested that the BDNF, CCK and TAC1 genes are associated with learning and memory in canines. Experimental validation is crucial to confirm the effects of these candidate genes on trainability. Understanding the genetic foundation of this trait would offer insight into the inheritance pattern of complex behavioural characteristics.

Objective

This study aimed to assess the genetic variations within candidate genes and explore their potential associations with behavioural phenotypes in dogs.

Methods

The behavioural characteristics of 123 male Belgian Ma

SUBMITTER: Fallahi M 

PROVIDER: S-EPMC10790320 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature