Factors associated with SARS-CoV-2 infection in unvaccinated children and young adults.

ABSTRACT:

Background and objectives

Pediatric COVID-19 cases are often mild or asymptomatic, which has complicated estimations of disease burden using existing testing practices. We aimed to determine the age-specific population seropositivity and risk factors of SARS-CoV-2 seropositivity among children and young adults during the pandemic in British Columbia (BC).

Methods

We conducted two cross-sectional serosurveys: phase 1 enrolled children and adults < 25 years between November 2020-May 2021 and phase 2 enrolled children < 10 years between June 2021-May 2022 in BC. Participants completed electronic surveys and self-collected finger-prick dried blood spot (DBS) samples. Samples were tested for immunoglobulin G antibodies against ancestral spike protein (S). Descriptive statistics f

SUBMITTER: Silverberg SL 

PROVIDER: S-EPMC10790408 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature