Genomic characterization of the C. tuberculostearicum species complex, a prominent member of the human skin microbiome.

ABSTRACT:

Importance

Amplicon sequencing data combined with isolate whole genome sequencing have expanded our understanding of Corynebacterium on the skin. Healthy human skin is colonized by a diverse collection of Corynebacterium species, but Corynebacterium tuberculostearicum predominates on many skin sites. Our work supports the emerging idea that C. tuberculostearicum is a species complex encompassing several distinct species. We produced a collection of genomes that help define this complex, including a potentially new species we term Corynebacterium hallux based on a preference for sites on the feet, whole-genome average nucleotide identity, pangenomic analysis, and growth in skin-like media. This isolate collection and high-quality genome resource se

SUBMITTER: Ahmed N 

PROVIDER: S-EPMC10790575 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature