Gut microbiome and antibiotic resistance effects during travelers' diarrhea treatment and prevention.

ABSTRACT:

Importance

The travelers' gut microbiome is potentially assaulted by acute and chronic perturbations (e.g., diarrhea, antibiotic use, and different environments). Prior studies of the impact of travel and travelers' diarrhea (TD) on the microbiome have not directly compared antibiotic regimens, and studies of different antibiotic regimens have not considered travelers' microbiomes. This gap is important to be addressed as the use of antibiotics to treat or prevent TD-even in moderate to severe cases or in regions with high infectious disease burden-is controversial based on the concerns for unintended consequences to the gut microbiome and antimicrobial resistance (AMR) emergence. Our study addresses this by evaluating the impact of defined antibiotic regimens (single-dose treatmen

SUBMITTER: Blake KS 

PROVIDER: S-EPMC10790752 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature