Considerations for hormonal therapy in migraine patients: a critical review of current practice.

ABSTRACT:

Introduction

Migraine, a neurovascular headache disorder, is a leading cause of disability worldwide. Within the multifaceted pathophysiology of migraine, hormonal fluctuations play an evident triggering and exacerbating role, pointing toward the need for identification and proper usage of both existing and new hormonal targets in migraine treatment.

Areas covered

With a threefold higher incidence of migraine in women than in men, the authors delve into sex hormone-related events in migraine patients. A comprehensive overview is given of existing hormonal therapies, including oral contraceptives, intrauterine devices, transdermal and subcutaneous estradiol patches, gnRH-agonists, oral testosterone, and 5α reductase inhibitors. The authors discuss their effectiveness and risk

SUBMITTER: van Lohuizen R 

PROVIDER: S-EPMC10791067 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature