Circulating immunophenotypes are potentially prognostic in follicular cell-derived thyroid cancer.

ABSTRACT:

Background

Exploring the immune interface of follicular cell-derived thyroid cancer has prognostic and therapeutic potential. The available literature is lacking for comprehensive immunophenotyping in relation to clinical outcomes. In this study, we identify circulating immunophenotypes associated with thyroid cancer prognosis.

Methods

We conducted a pilot observational study of adults with follicular cell-derived thyroid cancer who underwent surgery at our tertiary care referral center and had consented for flow cytometry on peripheral blood collected at the time of thyroidectomy.

Results

Of the 32 included subjects, 20 (62%) had well differentiated, 5 (16%) had poorly differentiated, and 7 (22%) had anaplastic thyroid cancer. The most frequent AJCC stage was 4 (59%)

SUBMITTER: Kotwal A 

PROVIDER: S-EPMC10792034 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature