Parathyroidectomy and the Risk of Major Cerebrovascular and Cardiovascular Events in the Elderly.

ABSTRACT:

Objective

We aimed to determine the incidence of major cardiovascular and cerebrovascular events in elderly patients with primary hyperparathyroidism (pHPT) and the impact of parathyroidectomy.

Summary background data

pHPT is underdiagnosed and undertreated in the United States. It is associated with increased cardiovascular disease risk, but its association with cerebrovascular disease risk is not well-established. It is also unknown if parathyroidectomy reduces these risks.

Methods

The incidence of major cerebrovascular and cardiovascular events in 108,869 patients with pHPT diagnosed in the Medicare database between 2008 and 2018 and a matched comparison group of 1,088,690 Medicare subjects was prospectively evaluated. We estimated hazard ratios (HR) for the associ

SUBMITTER: Grant RRC 

PROVIDER: S-EPMC10792119 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature