Investigating the Cytotoxicity of Ru(II) Polypyridyl Complexes by Changing the Electronic Structure of Salicylaldehyde Ligands.

ABSTRACT: A novel class of Ru(II)-based polypyridyl complexes with an auxiliary salicylaldehyde ligand [Ru(phen)₂(X-Sal)]BF₄ {X: H (1), 5-Cl (2), 5-Br (3), 3,5-Cl₂ (4), 3,5-Br₂ (5), 3-Br,5-Cl (6), 3,5-I₂ (7), 5-NO₂ (8), 5-Me (9), 4-Me (10), 4-OMe (11), and 4-DEA (12), has been synthesized and characterized by elemental analysis, FT-IR, and ¹H/¹³C NMR spectroscopy. The molecular structure of 4, 6, 9, 10, and 11 was determined by single-crystal X-ray diffraction analysis which revealed structural similarities. DFT and TD-DFT calculations showed that they also possess similar electronic structures.

SUBMITTER: Taghizadeh Shool M 

PROVIDER: S-EPMC10792608 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature