Pharmaceutical characterization and exploration of Arkeshwara rasa in MDA-MB-231 cells.

ABSTRACT:

Background

The diverse specificity mode of cancer treatment targets and chemo resistance demands the necessity of drug entities which can address the devastating dynamicity of the disease.

Objectives

To check the anti-tumour potential of traditional medicine rich in polyherbal components and metal nanoparticle namely Arkeshwara rasa (AR).

Material methods

The AR was prepared in a modified version with reference from Rasaratna Samuchaya and characterized using sophisticated instrumental analysis including XRD, SEM-EDAX, TEM, TGA-DSC, and LC-MS and tested against the MDA-MB-231 cell line to screen cell viability and the cytotoxicity with MTT, SRB and the AO assay.

Results

XRD pattern shows cubic tetrahedrite structure with Sb, Cu, S peaks and trace elements like

SUBMITTER: Jayakumar R 

PROVIDER: S-EPMC10792653 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature