Genomic data integration tutorial, a plant case study.

ABSTRACT:

Background

The ongoing evolution of the Next Generation Sequencing (NGS) technologies has led to the production of genomic data on a massive scale. While tools for genomic data integration and analysis are becoming increasingly available, the conceptual and analytical complexities still represent a great challenge in many biological contexts.

Results

To address this issue, we describe a six-steps tutorial for the best practices in genomic data integration, consisting of (1) designing a data matrix; (2) formulating a specific biological question toward data description, selection and prediction; (3) selecting a tool adapted to the targeted questions; (4) preprocessing of the data; (5) conducting preliminary analysis, and finally (6) executing genomic data integration.

Conc

SUBMITTER: Mardoc E 

PROVIDER: S-EPMC10792847 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature