Immunogenicity of a recombinant plant-produced respiratory syncytial virus F subunit vaccine in mice.

ABSTRACT: Respiratory syncytial virus (RSV) is a highly infectious respiratory virus that causes serious illness, particularly in young children, elderly people, and those with immunocompromised individuals. RSV infection is the leading cause of infant hospitalization and can lead to serious complications such as pneumonia and bronchiolitis. Currently, there is an RSV vaccine approved exclusively for the elderly population, but no approved vaccine specifically designed for infants or any other age groups. Therefore, it is crucial to continue the development of an RSV vaccine specifically tailored for these populations. In this study, the immunogenicity of the two plant-produced RSV-F Fc fusion proteins (Native construct and structural stabilized construct) were examined to assess them as potential v

SUBMITTER: Pisuttinusart N 

PROVIDER: S-EPMC10793081 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature