Multicenter evaluation of the Selux Next-Generation Phenotyping antimicrobial susceptibility testing system.

ABSTRACT: The Selux Next-Generation Phenotyping (NGP) system (Charlestown, MA) is a new antimicrobial susceptibility testing system that utilizes two sequential assays performed on all wells of doubling dilution series to determine MICs. A multicenter evaluation of the performance of the Selux NGP system compared with reference broth microdilution was conducted following FDA recommendations and using FDA-defined breakpoints. A total of 2,488 clinical and challenge isolates were included; gram-negative isolates were tested against 24 antimicrobials, and gram-positive isolates were tested against 15 antimicrobials. Data is provided for all organism-antimicrobial combinations evaluated, including those that did and did not meet FDA performance requirements. Overall very major error and major error rate

SUBMITTER: Baker KR 

PROVIDER: S-EPMC10793272 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature