Multi-contrast high-field quality image synthesis for portable low-field MRI using generative adversarial networks and paired data.

ABSTRACT:

Introduction

Portable low-field strength (64mT) MRI scanners promise to increase access to neuroimaging for clinical and research purposes, however these devices produce lower quality images compared to high-field scanners. In this study, we developed and evaluated a deep learning architecture to generate high-field quality brain images from low-field inputs using a paired dataset of multiple sclerosis (MS) patients scanned at 64mT and 3T.

Methods

A total of 49 MS patients were scanned on portable 64mT and standard 3T scanners at Penn (n=25) or the National Institutes of Health (NIH, n=24) with T1-weighted, T2-weighted and FLAIR acquisitions. Using this paired data, we developed a generative adversarial network (GAN) architecture for low- to high-field image translation (Low

SUBMITTER: Lucas A 

PROVIDER: S-EPMC10793526 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature